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http://hdl.handle.net/11154/1031
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| Title: | Study of chlorambucil and chlorambucil-trimethyl-beta-cyclodextrin inclusion complex by CE |
| Authors: | Balboa, MAH
Arevalo, VV
Reyes, VHA
Velazquez, AM
Ganem-Quintanar, A
Quintanar, D
Camacho, B
Arzaluz, GN
Rosales-Hoz, M
Leyva, MA
Angeles, E |
| Issue Date: | 2008 |
| Abstract: | The results of CE studies of solid inclusion complexes of chlorambucil (CHL) and trimethyl-beta-cyclodextrin (TM-beta-CD) are presented. Chlorambucil has low stability in aqueous solution, so the formation of complexes with beta-CD is a good way to improve its stability and dissolution. The experimental results confirm the existence of inclusion complexes. CE can differentiate free CHL from CHL-TM-beta-CD complexes due to their different electrophoretic mobilities. |
| URI: | http://hdl.handle.net/11154/1031 |
| ISSN: | 0009-5893 |
| Appears in Collections: | Ciencias
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