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Repositorio Atenea de la Facultad de Ciencias, UNAM >
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http://hdl.handle.net/11154/1150
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| Title: | Hypoglycemic effect of Toumefortia hirsutissima L., on n-streptozotocin diabetic rats |
| Authors: | Revilla-Monsalve, C
Wiedenfeld, H
Andrade-Cetto, Adolfo |
| Issue Date: | 2007 |
| Abstract: | The hypoglycemic effect of aqueous and butanolic extracts from Tournefortia hirsutissima (Boraginaceae) was determined on neonatal induced streptozotocin diabetic rats (n-STZ). Oral administration of water extracts at doses of 20 and 80 mg/kg, and butanolic extracts (8 and 80 mg/kg) significantly lowered the plasma glucose levels in diabetic rats within 3 It. Glibenclamide was used as reference and showed similar hypoglycemic effect. Our results support the traditional use of the plant as a hypoglycemic agent
we observe a dose-dependent action of the extracts. HPLC analysis confirmed that the aqueous and butanolic extracts had the same chemical composition. (C) 2007 Elsevier Ireland Ltd. All rights reserved. |
| URI: | http://hdl.handle.net/11154/1150 |
| ISSN: | 3788741 |
| Appears in Collections: | Departamento de Biología Celular
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