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Repositorio Atenea de la Facultad de Ciencias, UNAM >
Colecciones Ciencias >
Medicina UNAM >
Laboratorio de Inmunoparasitología >
Artículos sobre cisticercosis y T. solium publicados por investigadores mexicanos >
Please use this identifier to cite or link to this item:
http://hdl.handle.net/11154/174390
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| Title: | Induction of protection against porcine cysticercosis by vaccination with recombinant oncosphere antigens |
| Authors: | Flisser, A
Gauci, CG.
Zoli, A.
Martinez-Ocana, J.
Garza-Rodriguez, A.
Dominguez-Alpizar, JL.
Maravilla, P.
Rodriguez-Canul, R.
Avila , G.
Aguilar-Vega, L.
Kyngdon, C.
Geerts, S.
Lightowlers, MW |
| Issue Date: | 2004 |
| Publisher: | Infection and Immunity |
| Citation: | Flisser, A; Gauci, CG; Zoli, A; Martinez-Ocana, J; Garza-Rodriguez, A; Dominguez-Alpizar, JL; Maravilla, P; Rodriguez-Canul, R; Avila , G; Aguilar-Vega, L; Kyngdon, C; Geerts, S; Lightowlers, MW. (2004). Induction of protection against porcine cysticercosis by vaccination with recombinant oncosphere antigens. Infection and Immunit, 72(9), 5292-5297. |
| Abstract: | Two recombinant Taenia solium oncosphere antigens, designated TSOL18 and TSOL45-1A, were investigated as vaccines to prevent transmission of the zoonotic disease cysticercosis through pigs. Both antigens were effective in inducing very high levels of protection (up to 100%) in three independent vaccine trials in pigs against experimental challenge infection with T. solium eggs, which were undertaken in Mexico and Cameroon. This is the highest level of protection that has been achieved against T. solium infection in pigs by vaccination with a defined antigen. TSOL18 and TSOL45-1A provide the basis for development of a highly effective practical vaccine that could assist in the control and, potentially, the eradication of human neurocysticercosis. |
| URI: | http://hdl.handle.net/11154/99934
10.1128/IAI.72.9.5292-5297.2004
http://hdl.handle.net/11154/174390 |
| ISSN: | 0019-9567 |
| Appears in Collections: | Artículos sobre cisticercosis y T. solium publicados por investigadores mexicanos
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