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Artículos sobre cisticercosis y T. solium publicados por investigadores mexicanos >

Please use this identifier to cite or link to this item: http://hdl.handle.net/11154/174495

Title: Mutation at the HPRT locus in patients with neurocysticercosis treated with Praziquantel
Authors: Montero, R
Flisser, A
Madrazo, I
Cuevas, C
Ostrosky Wegman, P
Issue Date: 1994
Publisher: Mutation Reseearch
Citation: Montero, R; Flisser, A; Madrazo, I; Cuevas, C; Ostrosky Wegman, P. (1994). Mutation at the HPRT locus in patients with neurocysticercosis treated with Praziquantel. Mutation Reseearch, 305(2), 181-188.
Abstract: Praziquantel (PZQ) is the drug of choice in the treatment of neurocysticercosis (NC), a parasitic disease caused by Taenia solium larvae. Variant frequencies at the hprt locus were analyzed in a group of NC patients before and after treatment with PZQ as well as in two control groups: healthy donors and non-parasitic neurological patients. Data show that PZQ does no induce hprt mutations, but that cysticerci by themselves or together with palliative treatment administered to NC patients could induce mutations in some patients.
URI: http://hdl.handle.net/11154/99957
10.1016/0027-5107(94)90238-0
http://hdl.handle.net/11154/174495
ISSN: 0921-8262
Appears in Collections:Artículos sobre cisticercosis y T. solium publicados por investigadores mexicanos

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