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http://hdl.handle.net/11154/174495
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Title: | Mutation at the HPRT locus in patients with neurocysticercosis treated with Praziquantel |
Authors: | Montero, R Flisser, A Madrazo, I Cuevas, C Ostrosky Wegman, P |
Issue Date: | 1994 |
Publisher: | Mutation Reseearch |
Citation: | Montero, R; Flisser, A; Madrazo, I; Cuevas, C; Ostrosky Wegman, P. (1994). Mutation at the HPRT locus in patients with neurocysticercosis treated with Praziquantel. Mutation Reseearch, 305(2), 181-188. |
Abstract: | Praziquantel (PZQ) is the drug of choice in the treatment of neurocysticercosis (NC), a parasitic disease caused by Taenia solium larvae. Variant frequencies at the hprt locus were analyzed in a group of NC patients before and after treatment with PZQ as well as in two control groups: healthy donors and non-parasitic neurological patients. Data show that PZQ does no induce hprt mutations, but that cysticerci by themselves or together with palliative treatment administered to NC patients could induce mutations in some patients. |
URI: | http://hdl.handle.net/11154/99957 10.1016/0027-5107(94)90238-0 http://hdl.handle.net/11154/174495 |
ISSN: | 0921-8262 |
Appears in Collections: | Artículos sobre cisticercosis y T. solium publicados por investigadores mexicanos
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