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http://hdl.handle.net/11154/2882
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Title: | Methyl 4-hydroxy-3-(3'-methyl-2'-butenyl)benzoate, major insecticidal principle from Piper guanacastensis |
Authors: | PeredaMiranda, R Bernard, CB Durst, T Arnason, JT Poveda, L SanRoman, L SánchezVindas, P |
Issue Date: | 1997 |
Abstract: | The CHCl3-soluble extract of Piper guanacastensis (Piperaceae) was found to have noteworthy insecticidal activity to Aedes atropalpus mosquito larvae (LC(50) 80.5 mu g/mL). Bioassay-guided fractionation afforded methyl 4-hydroxy-3-(3'-methyl-2'-butenyl)benzoate (1) as the major bioactive constituent (LC(50) 20.5 mu g/mL). The separation of compound 1 from its transesterification artifact (2), ethyl 4-hydroxy-3-(3'-methyl-2'-butenyl)benzoate was achieved by recycling reversed-phase HPLC. The flavonoids acacetin, chrysin, and pinostrobin were also isolated from the active fraction but did not display insecticidal properties. |
URI: | http://hdl.handle.net/11154/2882 |
ISSN: | 0163-3864 |
Appears in Collections: | Ciencias
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