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Please use this identifier to cite or link to this item: http://hdl.handle.net/11154/3240

Title: Changes in the presence of progesterone receptor isoforms in the oviduct magnum of newly-hatched chicks after gonadotropins treatment
Authors: Camacho-Arroyo, I
González-Moran, G
Issue Date: 2003
Abstract: The effects of Follicle-stimulating hormone (FSH) and Luteinizing hormone (LH) on progesterone receptor (PR) isoforms presence in different cell populations from the oviduct magnum of newly-hatched chicks treated in vivo on days 13, 15 and 17 of embryonic development, were analyzed by immunohistochemistry. We found that FSH promoted cytodifferentiation of the magnum's mucosa and increased PR immunoreactivity in all cell types of the oviduct magnum, whereas LH-treatment did not exert cytodifferentiation of magnum's mucosa, and PR immunoreactivity was only induced in some epithelial and stromal cells of the oviduct magnum. In all treatments the number of PR immunopositive cells incubated with the antibody PgR Ab-8 that recognizes both PR isoforms were significantly higher than the number of immunopositive cells incubated with antibody PgR Ab-6 that only recognizes PR-B. This suggests that PR-A should be the predominant isoform in the oviduct magnum of newly-hatched chicks treated with gonadotropins during embryonic development. We conclude that gonadotropins differentially regulate PR-A isoform presence in the oviduct magnum of newly-hatched chicks. (C) 2003 Elsevier Science Inc. All rights reserved.
URI: http://hdl.handle.net/11154/3240
ISSN: 0024-3205
Appears in Collections:Ciencias

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