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Browsing by Author "Funes, S"

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Genetic correction of mitochondrial diseases - Using the natural migration of mitochondrial genes to the nucleus in chLorophyte algae as a model system

Funes, S; Perez-Martínez, X; Reyes-Prieto, A; Claros, MG; Davidson, E; King, MP; González-Halphen, D (2004)

Mitochondrial diseases display great diversity in clinical symptoms and biochemical characteristics. Although mtDNA mutations have been identified in many patients, there are currently no effective treatments. A number of ...
Subunit II of cytochrome c oxidase in chlamydomonad algae is a heterodimer encoded by two independent nuclear genes

Perez-Martínez, X; Antaramian, A; Vazquez-Acevedo, M; Funes, S; Tolkunova, E; d'Alayer, J; Claros, MG; Davidson, E; King, MP; González-Halphen, D (2001)

The mitochondrial genomes of Chlamydomonad algae lack the cox2 gene that encodes the essential subunit COX II of cytochrome c oxidase. COX II is normally a single polypeptide encoded by a single mitochondrial gene. In this ...
The typically mitochondrial DNA-encoded ATP6 subunit of the F1F0-ATPase is encoded by a nuclear gene in Chlamydomonas reinhardtii

Funes, S; Davidson, E; Claros, MG; van Lis, R; Perez-Martínez, X; Vazquez-Acevedo, M; King, MP; González-Halphen, D (2002)

The atp6 gene, encoding the ATP6 subunit of F1F0-ATP synthase, has thus far been found only as an mtDNA-encoded gene. However, atp6 is absent from mtDNAs of some species, including that of Chlamydomonas reinhardtii. Analysis ...
Unusual location of a mitochondrial gene - Subunit III of cytochrome c oxidase is encoded in the nucleus of chlamydomonad algae

Perez-Martínez, X; Vazquez-Acevedo, M; Tolkunova, E; Funes, S; Claros, MG; Davidson, E; King, MP; González-Halphen, D (2000)

The algae of the family Chlamydomonadaceae lack the gene cox3 that encodes subunit III of cytochrome c oxidase in their mitochondrial genomes. This observation has raised the question of whether this subunit is present in ...

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