Browsing by Subject "hypercholesterolemic diet"

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Comparative toxicity of high doses of vastatins currently used by clinicians, in CD-1 male mice fed with a hypercholesterolemic diet

Diaz-Zagoya, JC; Asenjo-Barron, JC; Martínez, F; Juárez-Oropeza, MA; Cárdenas-Vázquez, R (1999)

The CD-1 male-mouse model was employed to evaluate comparatively the toxicity of four vastatins (VTS) currently used in clinical medicine: lovastatin (LVT), simvastatin (SVT), pravastatin (PVT) and fluvastatin (FVT). Each ...
High lovastatin doses combined with hypercholesterolemic diet induce hepatic damage and are lethal to the CD-1 mouse

Asenjo-Barron, JC; Martínez, F; Diaz-Zagoya, JC; Juárez-Oropeza, MA; Cárdenas-Vázquez, R (1999)

The addition of 1% lovastatin (LVT) to hypercholesterolemic diets [1% cholesterol or 1% cholesterol plus 0.1% sodium deoxycholate (HD)] induced hepatic damage and was lethal to CD-1 mice in the first days of treatment

Now showing items 1-2 of 2

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