| dc.contributor.author |
Balboa, MAH |
|
| dc.contributor.author |
Arevalo, VV |
|
| dc.contributor.author |
Reyes, VHA |
|
| dc.contributor.author |
Velazquez, AM |
|
| dc.contributor.author |
Ganem-Quintanar, A |
|
| dc.contributor.author |
Quintanar, D |
|
| dc.contributor.author |
Camacho, B |
|
| dc.contributor.author |
Arzaluz, GN |
|
| dc.contributor.author |
Rosales-Hoz, M |
|
| dc.contributor.author |
Leyva, MA |
|
| dc.contributor.author |
Angeles, E |
|
| dc.date.accessioned |
2011-01-22T10:26:12Z |
|
| dc.date.available |
2011-01-22T10:26:12Z |
|
| dc.date.issued |
2008 |
|
| dc.identifier.issn |
0009-5893 |
|
| dc.identifier.uri |
http://hdl.handle.net/11154/1031 |
|
| dc.description.abstract |
The results of CE studies of solid inclusion complexes of chlorambucil (CHL) and trimethyl-beta-cyclodextrin (TM-beta-CD) are presented. Chlorambucil has low stability in aqueous solution, so the formation of complexes with beta-CD is a good way to improve its stability and dissolution. The experimental results confirm the existence of inclusion complexes. CE can differentiate free CHL from CHL-TM-beta-CD complexes due to their different electrophoretic mobilities. |
en_US |
| dc.language.iso |
en |
en_US |
| dc.title |
Study of chlorambucil and chlorambucil-trimethyl-beta-cyclodextrin inclusion complex by CE |
en_US |
| dc.type |
Article |
en_US |
| dc.identifier.idprometeo |
998 |
|
| dc.identifier.doi |
10.1365/s10337-007-0477-2 |
|
| dc.source.novolpages |
67(40545):193-196 |
|
| dc.subject.wos |
Biochemical Research Methods |
|
| dc.subject.wos |
Chemistry, Analytical |
|
| dc.description.index |
WoS: SCI, SSCI o AHCI |
|
| dc.subject.keywords |
capillary electrophoresis |
|
| dc.subject.keywords |
inclusion complexes |
|
| dc.subject.keywords |
trimethyl-b-cyclodextrin |
|
| dc.subject.keywords |
chlorambucil |
|
| dc.relation.journal |
Chromatographia |
|