Hypoglycemic effect of Toumefortia hirsutissima L., on n-streptozotocin diabetic rats

dc.contributor.author	Revilla-Monsalve, C
dc.contributor.author	Wiedenfeld, H
dc.contributor.author	Andrade-Cetto, Adolfo
dc.date.accessioned	2011-01-22T10:26:17Z
dc.date.available	2011-01-22T10:26:17Z
dc.date.issued	2007
dc.identifier.issn	3788741
dc.identifier.uri	http://hdl.handle.net/11154/1150
dc.description.abstract	The hypoglycemic effect of aqueous and butanolic extracts from Tournefortia hirsutissima (Boraginaceae) was determined on neonatal induced streptozotocin diabetic rats (n-STZ). Oral administration of water extracts at doses of 20 and 80 mg/kg, and butanolic extracts (8 and 80 mg/kg) significantly lowered the plasma glucose levels in diabetic rats within 3 It. Glibenclamide was used as reference and showed similar hypoglycemic effect. Our results support the traditional use of the plant as a hypoglycemic agent	en_US
dc.description.abstract	we observe a dose-dependent action of the extracts. HPLC analysis confirmed that the aqueous and butanolic extracts had the same chemical composition. (C) 2007 Elsevier Ireland Ltd. All rights reserved.	en_US
dc.language.iso	en	en_US
dc.title	Hypoglycemic effect of Toumefortia hirsutissima L., on n-streptozotocin diabetic rats
dc.type	Artículo de investigación	en_US
dc.identifier.idprometeo	1165
dc.identifier.doi	10.1016/j.jep.2007.02.020
dc.source.novolpages	112(1):96-100
dc.subject.wos	Plant Sciences
dc.subject.wos	Chemistry, Medicinal
dc.subject.wos	Integrative & Complementary Medicine
dc.subject.wos	Pharmacology & Pharmacy
dc.description.index	WoS: SCI, SSCI o AHCI
dc.subject.keywords	Tournefortia hirsutissima
dc.subject.keywords	hypoglycemic effect
dc.subject.keywords	n-Streptozotocin diabetic rats
dc.subject.keywords	type 2 diabetes
dc.relation.journal	Journal of Ethnopharmacology
dc.description.Departamento	Departamento de Biología Comparada