dc.contributor.author |
Allan, JC |
|
dc.contributor.author |
Avila , G |
|
dc.contributor.author |
Noval, JG |
|
dc.contributor.author |
Flisser, A |
|
dc.contributor.author |
Craig , PS |
|
dc.date.accessioned |
2011-12-07T13:06:20Z |
|
dc.date.accessioned |
2014-01-28T15:16:52Z |
|
dc.date.available |
2011-12-07T13:06:20Z |
|
dc.date.available |
2014-01-28T15:16:52Z |
|
dc.date.issued |
1990 |
|
dc.identifier.citation |
Allan, JC; Avila , G; Noval, JG; Flisser, A; Craig , PS. (1990). Immunidiagnosis of taeniasis by croproantigen detection. Parasitology, 101, 473-477. |
|
dc.identifier.issn |
0031-1820 |
|
dc.identifier.uri |
http://hdl.handle.net/11154/99919 |
|
dc.identifier.uri |
http://hdl.handle.net/11154/174375 |
|
dc.description.abstract |
Immunodiagnostic tests for Taenia-specific faecal antigen based on polyclonal rabbit antisera against Taenia saginata or Taenia solium proglottid extracts in capture-type ELISA assays have been developed. Taenia-specific antigen was detected in detergent-solubilized faecal extracts from T. solium- and T. saginata-infected hosts. Coproantigen from T. solium-infected hamsters did not cross-react with faeces from rodents infected with Hymenolepis diminuta, H. citelli, H. microstoma, Necator americanus, Strongyloides ratti or Nematospiroides dubius and feaces from uninfected animals. When the T. saginata-capture ELISA was tested with faecal samples positive for T. solium antigen, no cross-reactions were obtained. However, faecal samples from humans infected with T. solium or T. saginata, including some with extremely low egg counts, were cross-reactive by either test. Nevertheless, considerably higher O.D. values were obtained with stool samples from Taenia patients compared to Hymenolepis nana-infected or uninfected individuals. Two individuals, infected with Taenia sp. and positive for coproantigens by ELISA, became antigen-negative 6 days after treatment with Niclosamide. The possibility of developing species-specific immunodiagnostic tests for human taeniasis through coproantigen detection is discussed. |
|
dc.language.iso |
en |
|
dc.publisher |
Parasitology |
|
dc.subject.classification |
562 |
|
dc.title |
Immunidiagnosis of taeniasis by croproantigen detection |
|
dc.type |
Article |
|
dc.relation.index |
WoS |
|