dc.contributor.author |
Yuste, F |
|
dc.contributor.author |
Ortiz, B |
|
dc.contributor.author |
Carrasco, A |
|
dc.contributor.author |
Peralta, M |
|
dc.contributor.author |
Quintero, L |
|
dc.contributor.author |
Walls, F |
|
dc.contributor.author |
Ruano, JLG |
|
dc.contributor.author |
Sánchez-Obregon, R |
|
dc.date.accessioned |
2011-01-22T10:27:29Z |
|
dc.date.available |
2011-01-22T10:27:29Z |
|
dc.date.issued |
2000 |
|
dc.identifier.issn |
0957-4166 |
|
dc.identifier.uri |
http://hdl.handle.net/11154/2042 |
|
dc.description.abstract |
Enantiomerically pure (R-1,S-2)- and (S-1,S-2)-2-amino alcohols can be easily synthesized by stereodivergent reduction of alpha'-(N-Boc)amino beta-keto sulfoxides (easily synthesized from readily available N-Boc amino eater hydrochlorides) with DIBAH (clr 82-92%) and DIBAH/ZnBr2 (de 80%), followed by hydrogenolysis of the C-S bond of the resulting hydroxy sulfoxides and final hydrolysis of the N-Boc protecting group. (C) 2000 Elsevier Science Ltd. All rights reserved. |
en_US |
dc.language.iso |
en |
en_US |
dc.title |
Synthesis of enantiomerically pure 2-amino alcohols from amino acids mediated by sulfoxides |
en_US |
dc.type |
Article |
en_US |
dc.identifier.idprometeo |
2457 |
|
dc.source.novolpages |
11(15):3079-3090 |
|
dc.subject.wos |
Chemistry, Inorganic & Nuclear |
|
dc.subject.wos |
Chemistry, Organic |
|
dc.subject.wos |
Chemistry, Physical |
|
dc.description.index |
WoS: SCI, SSCI o AHCI |
|
dc.relation.journal |
Tetrahedron-Asymmetry |
|