dc.contributor.author | Castelli, MV | |
dc.contributor.author | Cortes, JCG | |
dc.contributor.author | Escalante, AM | |
dc.contributor.author | Bah, M | |
dc.contributor.author | Pereda-Miranda, R | |
dc.contributor.author | Ribas, JC | |
dc.contributor.author | Zacchino, SA | |
dc.date.accessioned | 2011-01-22T10:26:52Z | |
dc.date.available | 2011-01-22T10:26:52Z | |
dc.date.issued | 2002 | |
dc.identifier.issn | 0032-0943 | |
dc.identifier.uri | http://hdl.handle.net/11154/2513 | |
dc.description.abstract | Sixteen convolvulaceous glycolipids selected from the tricolorin (1-7) and orizabin (8-16) series, proved to be strong in vitro inhibitors of the enzyme that catalyzes the synthesis of 1,3-beta-D-glucan, a major polymer of fungal cell-walls. Results provide an insight into function of the specific structures of these complex macrocyclic lactones as inhibitors of the 1,3-beta-D-glucan synthase and open the possibility of using these compounds as starting points for the development of antifungal agents that act by inhibiting fungal cell-wall synthesis. | en_US |
dc.language.iso | en | en_US |
dc.title | In vitro inhibition of 1,3-beta-glucan synthase by glycolipids from convolvulaceous species | en_US |
dc.type | Article | en_US |
dc.identifier.idprometeo | 2152 | |
dc.source.novolpages | 68(8):739-742 | |
dc.subject.wos | Plant Sciences | |
dc.subject.wos | Chemistry, Medicinal | |
dc.subject.wos | Pharmacology & Pharmacy | |
dc.description.index | WoS: SCI, SSCI o AHCI | |
dc.relation.journal | Planta Medica |
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