Effect of Kauranes from Montanoa spp on rat uterus

dc.contributor.author	CamposBedolla, P
dc.contributor.author	Campos, MG
dc.contributor.author	PonceMonter, H
dc.contributor.author	Uribe, C
dc.contributor.author	Osuna, L
dc.contributor.author	Calderon, J
dc.contributor.author	ValenciaSánchez, A
dc.date.accessioned	2011-01-22T10:27:57Z
dc.date.available	2011-01-22T10:27:57Z
dc.date.issued	1997
dc.identifier.issn	0951-418X
dc.identifier.uri	http://hdl.handle.net/11154/2917
dc.description.abstract	The effect of kaurenoic acid (from Montanoa frutescens), grandifloric and kauradienoic acid (from M. tomentosa) and 16 alpha-hydroxy-ent-kauran-19-oic acid and its methyl ester (from M. hibiscifolia) were assayed on the contractions of rat uterus induced by acetylcholine, oxytocin and serotonin. The four kauranes assayed inhibited the contractile activity induced by the three agonists through a mechanism independent of either beta(2)-adrenergic or H-2-histaminergic receptors present in uterine smooth muscle. Oestrogenized uteri treated with kauradienoic acid underwent histological changes including epithelial flattening and desquamation. (C) 1997 by John Wiley & Sons, Ltd.	en_US
dc.language.iso	en	en_US
dc.title	Effect of Kauranes from Montanoa spp on rat uterus	en_US
dc.type	Article	en_US
dc.identifier.idprometeo	3012
dc.source.novolpages	11(1):11-16
dc.subject.wos	Chemistry, Medicinal
dc.subject.wos	Pharmacology & Pharmacy
dc.description.index	WoS: SCI, SSCI o AHCI
dc.subject.keywords	Montanoa
dc.subject.keywords	zoapatle
dc.subject.keywords	kauranes
dc.subject.keywords	rat uterus
dc.subject.keywords	smooth muscle
dc.relation.journal	Phytotherapy Research