dc.contributor.author |
COCHO, G |
|
dc.contributor.author |
GELOVER, A |
|
dc.contributor.author |
BULAJICH, R |
|
dc.contributor.author |
MartínezMEKLER, G |
|
dc.date.accessioned |
2011-01-22T10:28:45Z |
|
dc.date.available |
2011-01-22T10:28:45Z |
|
dc.date.issued |
1992 |
|
dc.identifier.issn |
0035-001X |
|
dc.identifier.uri |
http://hdl.handle.net/11154/3522 |
|
dc.description.abstract |
The evolution of genetic sequences, in particular the case of retro-virus as encountered in AIDS, is analyzed by means of a coupled Map lattice model. Mutations are introduced as coupling terms and several ecological constraints are considered. The resulting equations are of the reaction-diffusion type. The model establishes an evolution fitness criteria in terms of dynamical and structural properties at the molecular level. Under a global ecological constraint, the model dynamics generates quasi-species and presents an error threshold. Qualitative predictions regarding the AIDS vims RNA stability under mutations are corroborated experimentally. |
en_US |
dc.language.iso |
en |
en_US |
dc.title |
MODELING GENETIC EVOLUTION WITH COUPLED MAP LATTICES |
en_US |
dc.type |
Article |
en_US |
dc.identifier.idprometeo |
3395 |
|
dc.source.novolpages |
38:127-141 |
|
dc.subject.wos |
Physics, Multidisciplinary |
|
dc.description.index |
WoS: SCI, SSCI o AHCI |
|
dc.relation.journal |
Revista Mexicana De Fisica |
|