Chromatin structure contribution to the synaptonemal complex formation

DSpace/Manakin Repository

Show simple item record Hernandez-Hernandez, A Echeverria, OM Félix Recillas, T Vázquez-Nin, Gerardo Hebert 2011-01-22T10:25:53Z 2011-01-22T10:25:53Z 2009
dc.identifier.issn 1420682X
dc.description.abstract Meiosis is a key cellular and molecular process for sexual reproduction contributing to the genetic variability of organisms. This process takes place after DNA replication and consists in a double cellular division, giving rise to four haploid daughter cells or gametes. Meiotic recombination between homologous chromosomes, in the meiotic prophase I, is mediated by a tripartite structure named Synaptonemal Complex (SC). The SC is a peptidic scaffold in which the chromatin of homologous chromosomes is organized during the pachytene stage, holding chromosomes together until the meiotic recombination and genetic exchange have taken place. The role of chromatin structure in formation of the SC and the meiotic recombination at meiotic prophase I remain largely unknown. In this review we address the epigenome contribution to the SC formation at meiotic prophase I, with particular attention on the chromatin structure modifications occurring during the sub-stages of meiotic prophase I. en_US
dc.language.iso en en_US
dc.title Chromatin structure contribution to the synaptonemal complex formation
dc.type Artículo de investigación en_US
dc.identifier.idprometeo 594
dc.identifier.doi 10.1007/s00018-008-8584-2
dc.source.novolpages 66(7):1198-1208
dc.subject.wos Biochemistry & Molecular Biology
dc.subject.wos Cell Biology
dc.description.index WoS: SCI, SSCI o AHCI
dc.subject.keywords Synaptonemal complex
dc.subject.keywords chromatin structure
dc.subject.keywords epigenetic modification
dc.subject.keywords meiotic prophase I
dc.subject.keywords lateral element associated repeat sequences (LEARS)
dc.relation.journal Cellular and Molecular Life Sciences
dc.description.Departamento Departamento de Biología Comparada

Files in this item

Files Size Format View

There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record

Search DSpace

Advanced Search


My Account