dc.contributor.author |
Perez-Diaz, JOH |
|
dc.contributor.author |
Vega-Baez, JL |
|
dc.contributor.author |
Sandoval-Ramirez, J |
|
dc.contributor.author |
Meza-Reyes, S |
|
dc.contributor.author |
Montiel-Smith, S |
|
dc.contributor.author |
Farfan, N |
|
dc.contributor.author |
Santillan, R |
|
dc.date.accessioned |
2011-01-21T09:04:21Z |
|
dc.date.available |
2011-01-21T09:04:21Z |
|
dc.date.issued |
2010 |
|
dc.identifier.issn |
0039-128X |
|
dc.identifier.uri |
http://hdlhandlenet/123456789/175 |
|
dc.description.abstract |
The E ring regioselective acid-catalyzed opening of spirostanic sapogenins possessing a carbonyl group at C-12, such as botogenin and hecogenin, provided the new 12,23-cyclo-22,26-epoxycholesta-11,22-diene skeleton, in addition to new compounds of the already known 12,23-cyclocholest-12(23)-en-22-one frameworks. This transformation proceeds in a single step, under slightly acidic conditions. Both, penta- and hexacyclic steroids were obtained with retention of configuration of all asymmetric centers. (C) 2010 Elsevier Inc. All rights reserved. |
en_US |
dc.language.iso |
en |
en_US |
dc.title |
Novel steroidal penta- and hexacyclic compounds derived from 12-oxospirostan sapogenins |
en_US |
dc.type |
Article |
en_US |
dc.identifier.idprometeo |
35 |
|
dc.identifier.doi |
10.1016/j.steroids.2010.07.008 |
|
dc.source.novolpages |
75:1127-1136 |
|
dc.subject.wos |
Biochemistry & Molecular Biology |
|
dc.subject.wos |
Endocrinology & Metabolism |
|
dc.description.index |
WoS: SCI, SSCI o AHCI |
|
dc.subject.keywords |
12-Oxosapogenins |
|
dc.subject.keywords |
Polycyclic steroids |
|
dc.subject.keywords |
Intramolecular cyclocondensation |
|
dc.relation.journal |
Steroids |
|