dc.contributor.author |
Siodmiak, J |
|
dc.contributor.author |
Uher, JJ |
|
dc.contributor.author |
Kruszewska, N |
|
dc.contributor.author |
Gadomski, A |
|
dc.contributor.author |
Santamaria, I |
|
dc.date.accessioned |
2011-01-22T10:26:01Z |
|
dc.date.available |
2011-01-22T10:26:01Z |
|
dc.date.issued |
2007 |
|
dc.identifier.issn |
0092-0606 |
|
dc.identifier.uri |
http://hdl.handle.net/11154/980 |
|
dc.description.abstract |
A superdiffusive random-walk action in the depletion zone around a growing protein crystal is considered. It stands for a dynamic boundary condition of the growth process and competes steadily with a quasistatic, curvature-involving (thermodynamic) free boundary condition, both of them contributing to interpret the (mainly late-stage) growth process in terms of a prototype ion-channeling effect. An overall diffusion function contains quantitative signatures of both boundary conditions mentioned and indicates whether the new phase grows as an orderly phase or a converse scenario occurs. This situation can be treated in a quite versatile way both numerically and analytically, within a generalized Smoluchowski framework. This study can help in (1) elucidating some dynamic puzzles of a complex crystal formation vs biomolecular aggregation, also those concerning ion-channel formation, and (2) seeing how ion-channel-type dynamics of non-Markovian nature may set properly the pace of model (dis)ordered protein aggregation. |
en_US |
dc.language.iso |
en |
en_US |
dc.title |
On the protein crystal formation as an interface-controlled process with prototype ion-channeling effect |
en_US |
dc.type |
Article |
en_US |
dc.identifier.idprometeo |
839 |
|
dc.identifier.doi |
10.1007/s10867-008-9076-1 |
|
dc.source.novolpages |
33(4):313-329 |
|
dc.subject.wos |
Biophysics |
|
dc.description.index |
WoS: SCI, SSCI o AHCI |
|
dc.subject.keywords |
protein solution |
|
dc.subject.keywords |
protein crystal |
|
dc.subject.keywords |
electrostatic double layer |
|
dc.subject.keywords |
ion channel |
|
dc.subject.keywords |
enhanced diffusion |
|
dc.relation.journal |
Journal of Biological Physics |
|